Good stuff here, one of my favorite types of heroes.
Arachnids: I have a Silver Age scorpion based Spider-Man knock off called The Sting. A teenager vacationing in Las Vegas is stung by a scorpion irradiated by atomic testing. He gains the strength, invulnerability and abilities of a scorpion. He creates a 'stingline' (as teenagers of the time were known to do), a telescopic metal tendril with a paralytic poison delivery system and a cable claw that allows him to swing from building to building. My character Tarantula (the DC one) has a number of insect motiffed villains in his Rogue's Gallery. Trapdoor, a spider motiff villain that creates wormholes and favors sneak attacks. Another is Wasp Woman, cosmetic magnate that uses phermones to control men and wasps (based on a roger Corman flick). Finally there's Portia, which is a genus of wolf spider know for their cunning, a femme fatale ex-spy.
Canines: I had another roofrunner character called the Fox. He was the son of the heroine White Rabbit (A Black Canary type who could create warpholes) and the silver age Fox. His weapon was the Foxglove (gadget gauntlet) with fired the Foxtail (swingline) and Foxfire (flash). Like his mother, he could open warps, which he called 'foxholes'. His battle cry was Tallyho! As an alternative to the fox/wolf standards, I always thought Mastiff and Foxhound/Wolfhound could be cool themes.
Felines: I have a villain team called the Pride (which I had help creating via these boards): Siberian (Brick), Tomcat (Flying Power Armor), Snow Leopard (Ice Guy), Boots (cute girl gadgeteer), and Lioness (avatar of Sehkmet, Egyptian lion-headed goddess of war).
No one mentioned equines: Mustang, Bronco, Warhorse, Palamino...how about a St. Louis based hero named Clydesdale 
I highly recommend Animal Planet/Discovery Channel. Anyone know that platapus have poisonous stingers that produce one of the most painful venoms in the world. And I'm still going to do something with Funnelweb, named for the deadliest spider in the world.
As far as sheep...how about Counting Sheep, the sleep inducing villain!
Monster Island and Milwaukee are thousands of miles apart. Monster Island means gigantic mutant hellbeasts and 50 ft. cockroaches, and Milwaukee means beer. And on Monster Island, they don't take any crap and they don't take American Express.
Tom Servo, MST3K, Godzilla vs. Megalon
Now Venture will send Sampson after the rest of us, and he'll go totally sickhouse on our asses. I like my ass, gentlemen.
The Monarch addressing his henchmen, The Venture Bros.
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