Re: Shadow Angelus
In my original source material, Espers are not trusted ("After all, that chap can see what you're thinking!"), whilst Sorcerers are considered more of a celebrity status (due to the influence of stage magicians and pop culture).
The existence of Entities is not known to the public at large, it is the "big secret" that only those who need to know ever truly understand.
Keeping all of the above in mind, Espers are considered just above clades in the main public mindset: useful, creepy, barely-human. I would say that the life of an Esper is slightly better than in K5, but only very slightly. Espers tend to congregate in Angelus for a number of reasons, some known and others merely guessed at. In the "Ten Years After" timeline they ended up forming the IOTA foundation and congregated into a sector later renamed to "Psi."
In-game, there was definitely some prejudice and mistrust of espers, but it tended to be overshadowed by the larger concerns with the social class of clades, invasions by the Enochians and later the Entities, and other various things going on.
Hope all that helps!