I can only comment on the heroes in Champions: The Live-Action Roleplaying Game as it is the book on the shelf right next to me, but the following are heroes that appear in the book with ones submitted by backers in italics. The othe heroes may be from previous works, I apologize for not knowing where they may have come from or who deserves proper credit for these awesome guys.
Aurum, The Alchemist Frank Cho
Mighty Mite, Dean Anderson
Vanguard
Gemma Suzan
Demon Hunter, James Holt
Ankh, Professor Celene Garfield
Defender, James Harmon IV
Ironclad, Drogen Lar
Kinetik, Brendan Grant
Sapphire, Corazon "Corrie" Valenzuela
Witchcraft, Bethany Duquesne
Dr. Silverback