In a recent game I played, I could tell from the beginning of the adventure that it would wrap up in a warehouse full of vampires. I guess I was the nominal leader, so instead of following the usual trail, I almost immediately set half the group to go get a gasoline tanker truck (All they could find was propane). When they got back, we drove the tanker truck, followed by another car behind it (in case the truck didn't light), into the warehouse where it to managed to destroy all of the hench-vampires and a couple of weeks of planning on the part of the GM. Two key Vamps got out, but it was a lot better than it could've been. The GM couldn't get too upset because what we did made perfect sense.
Fionan.