Mass Destruction Paranormals
I have to admit, I've never really run with that. I tend to run more 70s style games, at least in tone, wherein supers weren't dumped on just for being supers. With the rare exception (your occassional bigot, basically), people will judge a super on his actions. Distinctive Features affects this, of course, and other things like villains plotting to make heroes look bad, but I've never had the government(s) do anything like a Registration or Licensing act.
However, I do generally rule that any crime that involves superpowers or supertech is considered to be a use of Weapons of Mass Destruction, meaning that any crime involving superpowers becomes a serious felony. A little something to help keep the PCs in line, mostly, since a missed shot isn't just 'negligence', it becomes a Weapons Of Mass Destruction deal, and thusly a *lot* more severe.