Re: PRE Drains
Ok, loser of losers. I use the PRE/EGO Drain combo as a means to represent turning somebody's psyche into silly-putty through some kind of overload, whether it be through fear, overwhelmingly guilt, Cthulhoid SAN-blasting, or what have you. The result of the double whammy Drain is that the poor fellow, once drained to negatives in both stats, is sitting in the corner screaming "oh god! oh god! the humanity!" He can't make any aggressive action, and he will obey anything you tell him.
In fact the character I'm finishing up building has just this power, defined as overwhelming the target with guilty memories of bad things he's done.