My Champions would be:
New Millenium Quantum: Tough, militaristic black female. Also would be leader of the team. Female team leaders intrigue me.
New Millenium Defender: I believe the Team: Defender concept is much more interesting that the Tony Stark rip-off. He is a college kid that would grow into his role on the team.
Seeker: I've always liked Seeker. He grew especially well, to the powered up version in the original CU, to his 'World Class martial artist' version in Watchers of the Dragon. A swashbuckling martial artist is excellent. I've never understood the complaints about his 'origin'. Explain to me how it is more strange than 'radioactive spider' or 'last alien from dying planet'?
Obsidian: Combines the 'fish out of water' element with the 'Noblesse Oblige'. Rather unique character I think.
Witchcraft: A copy of Solitaire? Yep. However, I prefer her costume, the evil sister angle, and she doesn't have the annoying triple identity/actress crisis.
*Also, I realize that the characters were made primarily as generic examples. Fine. Except they are routinely mentioned as a paramount team in the new Champions Universe. The ACTUAL canon version of the team for the current CU universe should be 450-500 point characters in my opinion.