My fictional city (originally created some ten years ago, real time) is called Trinity City, located at the confluence of the Mississippi and Ohio rivers, at the site of real-world Cairo, IL. The name of the city came from its history (as it grew ahistorically from extra railroads run into the area both antebellum and later) when the area suffered less from the Great Depression than cities further east, and FDR made a speech during the 1936 elections praising 'this trinity of cities' (at the time they were Cairo, IL, West Cairo, MO, and South Cairo, KY). Within six months each city had renamed itself Trinity City.
Ultimately, the three cities merged under one municipal government, but that's a tale for another day.