In Astro City, The First Family has three generations. Super Genius, Dr. Augustus Furst and his brother Julian started out (Augustus was still in his teens) in the fifties (I think) as explorers into the unkown, discovering hidden races, alternate dimensions and fighting monsters. Dr. Furst was married four times (maybe more, can't remember) and one of his wives left him for Kaspian, leader of the Beast-Men. Years later, his ex-wife died or disappeared and Augustus ended up adopting her and Kaspian's twin children Natalie and Nick. They were energy manipulators and joined Augustus and Julian on their adventures. Natalie married Rex who is Prince of Monstro City. He's like an aristocratic, refined Thing. Julian fills the gruff Uncle roll. Rex and Natalie had a daughter, Astra, adding generation three to the First Family. Astra's an energy projector as well, but even more powerful than her mom or Uncle Nick. Now this is a really cool, multi-generational super-team.